{"id":6220,"date":"2018-01-27T09:48:22","date_gmt":"2018-01-27T00:48:22","guid":{"rendered":"http:\/\/ircn.jp\/?page_id=6220"},"modified":"2019-02-22T09:11:38","modified_gmt":"2019-02-22T00:11:38","slug":"es-virus-core","status":"publish","type":"page","link":"https:\/\/ircn.jp\/en\/core-facilities\/es-virus-core","title":{"rendered":"ES-Mouse\/Virus Core"},"content":{"rendered":"<p><strong>Mission:<\/strong><br \/>\nThe ES-Mouse\/Virus Core houses facilities and services for the generation of genetically-modified mice, and the production of viruses for studies with genetically-modified mice.<\/p>\n<p><strong>Technology:<\/strong><br \/>\nThe core uses a highly efficient, rapid, and simple procedure for the production of ES mouse for genetically-modified and knock-in mice. The procedure enables the simultaneous production of multiple knock-in ES cells in about 1 month. The core also has the ability to create multiple parallel lines of knock-in ES mice without a need for the crossing of chimeric mice, thus shortening production time from about a year to 2-3 months.<\/p>\n<table style=\"height: 61px;\" border=\"0\">\n<tbody>\n<tr style=\"height: 61px;\" valign=\"top\">\n<td style=\"width: 304px; height: 61px;\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-medium wp-image-7620\" src=\"http:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/Fig-2-EnHP-300x188.jpg\" alt=\"\" width=\"300\" height=\"188\" srcset=\"https:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/Fig-2-EnHP-300x188.jpg 300w, https:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/Fig-2-EnHP-768x481.jpg 768w, https:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/Fig-2-EnHP-88x55.jpg 88w, https:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/Fig-2-EnHP.jpg 800w, https:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/Fig-2-EnHP-624x391.jpg 624w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/td>\n<td style=\"width: 190px; height: 61px;\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone wp-image-7619\" src=\"http:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/Fig-6-EnHP-284x300.jpg\" alt=\"\" width=\"186\" height=\"196\" srcset=\"https:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/Fig-6-EnHP-284x300.jpg 284w, https:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/Fig-6-EnHP-768x810.jpg 768w, https:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/Fig-6-EnHP-52x55.jpg 52w, https:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/Fig-6-EnHP-624x658.jpg 624w, https:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/Fig-6-EnHP.jpg 800w\" sizes=\"(max-width: 186px) 100vw, 186px\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Core Manager:<\/strong><br \/>\n<a href=\"https:\/\/www.researchgate.net\/profile\/Hideki_Ukai\" target=\"_blank\" rel=\"noopener\">Hideki Ukai, Ph.D.<\/a><br \/>\n<img decoding=\"async\" loading=\"lazy\" class=\"alignleft wp-image-7502 size-thumbnail\" src=\"http:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/f0a017748056cb990b6ae4df7ad0ae8b-e1528774991492-150x150.jpg\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/f0a017748056cb990b6ae4df7ad0ae8b-e1528774991492-150x150.jpg 150w, https:\/\/ircn.jp\/wp-content\/uploads\/2018\/06\/f0a017748056cb990b6ae4df7ad0ae8b-e1528774991492-54x55.jpg 54w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/p>","protected":false},"excerpt":{"rendered":"Mission: The ES-Mouse\/Virus Core houses facilities and services for the generation of genetically-modified mice, and the production of viruses for studies with genetically-modified mice. Technology: T [&hellip;]","protected":false},"author":1,"featured_media":0,"parent":7497,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_links_to":"","_links_to_target":""},"acf":[],"aioseo_notices":[],"jetpack_shortlink":"https:\/\/wp.me\/P9Xf4o-1Ck","_links":{"self":[{"href":"https:\/\/ircn.jp\/en\/wp-json\/wp\/v2\/pages\/6220"}],"collection":[{"href":"https:\/\/ircn.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ircn.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ircn.jp\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ircn.jp\/en\/wp-json\/wp\/v2\/comments?post=6220"}],"version-history":[{"count":14,"href":"https:\/\/ircn.jp\/en\/wp-json\/wp\/v2\/pages\/6220\/revisions"}],"predecessor-version":[{"id":7830,"href":"https:\/\/ircn.jp\/en\/wp-json\/wp\/v2\/pages\/6220\/revisions\/7830"}],"up":[{"embeddable":true,"href":"https:\/\/ircn.jp\/en\/wp-json\/wp\/v2\/pages\/7497"}],"wp:attachment":[{"href":"https:\/\/ircn.jp\/en\/wp-json\/wp\/v2\/media?parent=6220"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}