The ES-Mouse/Virus Core houses facilities and services for the generation of genetically-modified mice, and the production of viruses for studies with genetically-modified mice.
The core uses a highly efficient, rapid, and simple procedure for the production of ES mouse for genetically-modified and knock-in mice. The procedure enables the simultaneous production of multiple knock-in ES cells in about 1 month. The core also has the ability to create multiple parallel lines of knock-in ES mice without a need for the crossing of chimeric mice, thus shortening production time from about a year to 2-3 months.
Hideki Ukai, Ph.D.